en روانپزشكي Psychiatry گزارش مورد case report <p style="text-align: justify;"><strong>Objective:</strong> Obsessive-Compulsive disorder (OCD) is one of the greatest and debilitating&nbsp;disorders, which many of its patients do not respond to psychotherapy and pharmacotherapy.&nbsp;In this regard, paying attention to new treatments such as transcranial direct current stimulation&nbsp;(tDCS) is important. The purpose of the present research was to examine the effects of tDCS&nbsp;on the obsession-compulsion (OC), anxiety, and depression of a patient suffering from OCD.<br> <strong>Methods:</strong> The present study conducted on a 23-year-old female patient with OCD. tDCS&nbsp;sessions were lasted 10 days, one session per day and each session of about 20 minutes with 2.0&nbsp;mA intensity. The results of Beck depression inventory, Hamilton anxiety rating scale, and Yale&nbsp;Brown obsessive-compulsive scale showed decrease in OC, depression, and anxiety symptoms&nbsp;after 10 sessions of tDCS.<br> <strong>Results:</strong> The results of the present research using cathodal tDCS on orbitofrontal cortex in&nbsp;10 sessions showed that this montage is a powerful and successful treatment for patients with&nbsp;OCD and alleviate their OC, depression, and anxiety symptoms.<br> <strong>Conclusion:</strong> The data were analyzed by diagram analysis and improvement percentage. This&nbsp;study showed that anodal tDCS on O2 and cathodal tDCS on orbitofrontal cortex improved&nbsp;OC, anxiety and depression symptoms. However, our findings give introductory confirmation&nbsp;that our patient with OCD has a positive response to cathode tDCS of the OFC.</p> Anxiety, Depression, Transcranial direct current stimulation, Obsessioncompulsion 75 80 http://jpcp.uswr.ac.ir/browse.php?a_code=A-10-35-2&slc_lang=en&sid=1 Jaber Alizadeh Goradel j.alizadeh45@gmail.com No Young Researcher and Elite Club, Islamic Azad University, Ardabil Branch, Ardabil, Iran. Asghar Pouresmali asgharpouresmali@yahoo.com No Young Researcher and Elite Club, Islamic Azad University, Ardabil Branch, Ardabil, Iran. Mehri Mowlaie mehri.molaee@yahoo.com Yes Department of Psychology, Faculty of Education and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran. Fariba Sadeghi Movahed No Department of Psychiatry, School of Medicine & Allied Medical Sciences, Ardabil University of Medical Science, Ardabil, Iran.