en روانپزشكي Psychiatry پژوهشي Original Research Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><strong>Objective</strong>: The current COVID-19 pandemic is associated with numerous psychological issues, such as anxiety and distress as a result of individual, health-related, social, and economic issues. This study aims to assess the general population in Iran for the negative impacts of the current pandemic on psychological well-being and to find possible protective and risk factors when facing such situations in the current COVID-19 pandemic.<br> <strong>Methods</strong>: A total of 317 people participated in an online survey in Iran from August 3, 2020, to September 20, 2020. Anxiety, depression, fear of COVID-19, emotion regulation, intolerance of uncertainty, illness perception, neuroticism, social support, and self-efficacy were evaluated.&nbsp;<br> <strong>Results</strong>: The results showed that measures that assess anxiety, depression, emotion regulation, intolerance of uncertainty, illness perception, neuroticism, social support, and self-efficacy were significantly related to fear of COVID-19. Meanwhile, the results of regression analysis demonstrated that neuroticism, intolerance of uncertainty, and illness perception could predict fear of COVID-19 beyond and above anxiety and depression.<br> <strong>Conclusion</strong>: Some factors, including neuroticism, illness perception, and intolerance of uncertainty are considered risk factors for mental health during this pandemic. </span></span></span></div> COVID-19, Anxiety, Neuroticism, Intolerance of uncertainty, Illness Perception 167 176 http://jpcp.uswr.ac.ir/browse.php?a_code=A-10-853-1&slc_lang=en&sid=1 Imaneh Abasi abasi@sbmu.ac.ir 0000-0002-9822-8948 No Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Azin Farzin azinfarzings@gmail.com 0000-0001-6104-4670 Yes Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Amin Sohrabzadeh Fard sohrabzadhamin@yahoo.com No Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Abbas Masjedi Arani a.masjediarani@sbmu.ac.ir No Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Hamid Poursharifi ha.poursharifi@uswr.ac.ir No Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Mohammad Ebrahimzadeh Mousavi No Department of Human Development and Family Sciences, University of Delaware, Newark, United States. Ali Mehrabi No Department of Psychology, Faculty of Education and Psychology, University of Isfahan, Iran.